Theresa May will round off the Tory conference with an attempt to raise party morale and convince activists that the Conservatives are about more than Brexit.
Amid reports that cabinet ministers are urging her to set a date for her departure, she will claim Britain's future after leaving the European Union is full of promise.
She'll announce that fuel duty will be frozen for the ninth year in a row, in a move she claims demonstrates to families that the government is on their side.
And after a day in which Boris Johnson stole the show at the conference with his "chuck Chequers" onslaught, the Prime Minister will attempt to re-assert her authority.
Speaking before her speech, she told Sky News: "We do have the big ideas. We have to make the arguments for free markets, for open economies, and we have to recognise in doing that, that for some people as I said on the steps of Downing Street back when I first became prime minister, they do feel that things haven't been working for everyone in the way that they should.
"That's why alongside the discussions about Brexit, actually what this conference has been focusing on is the changes we're making to people in terms of things like putting extra money into social care, to ensure we're dealing with the winter pressures, to the commitment we've already made for more money for the National Health Service, the changes we're making in the apprenticeship levy, to ensure that we get those good apprenticeships available for our young people.
"These are all important ways in which we're dealing day to day with the issues that make a real difference to people's lives."
In an upbeat passage in her speech, she will say: "I passionately believe that our best days lie ahead of us and that our future is full of promise.
"Don't let anyone tell you we don't have what it takes: we have everything we need to succeed."
But with rumours circulating in Birmingham that the prime minister has a tickly cough, she will be hoping there is no repeat of the mishaps she suffered during her conference speech last year.
First, she was presented with a spoof P45 by a comedian sitting in the front row. Then she suffered a coughing fit she could not shake off. And then letters started to fall off the set behind her.
"Look, unpredictable things happen," Tory deputy chairman James Cleverly told Sky News.
"What we saw last year was two things: on the stage itself it was like a trial by ordeal and she fought through and she kept on fighting and she got to the end of the speech and the auditorium erupted.
"Then the thing we saw immediately afterwards was that tweet about the Strepsils and the speech and we laughed along with her and she showed that humorous side of her.
"That's what the party really respects, I think. That's what, that's one of her great strengths.
"She's got the fortitude, she's also got a little bit of humour. Sometimes it comes out, sometimes she hides it away, but she is a really strong woman, a really strong prime minister and I really hope that comes across in the speech."
On the eve of her speech, Boris Johnson infuriated the prime minister with a cultivated media scrum and then delighting his supporters with a speech in which he set out his personal Tory leadership manifesto and savaged her Chequers plan.
Condemning it as a "constitutional outrage, he had adoring supporters cheering wildly when he said: "Now is the time to chuck Chequers."
3:00Looking ahead to the PM's speech, Johnson ally Jacob-Rees Mogg told Sky News: "In an ideal world I'd like her to say that she's chucking Chequers and she's going to have a "super-Canada" deal.
"But I'm realistic and she's not going to say that. So I would like her to concentrate on domestic policy and what the Conservatives should be doing beyond Brexit: housing policy, financial policy, health policy.
"I think it's an opportunity for her to say that there is an opportunity beyond Brexit because I think Brexit is not going to be settled in her own mind and in the cabinet's mind until the next round of discussions with the European Union."
The prime minister will tell delegates that at this "moment of opportunity" the Conservatives will always act in the "national interest" and put the needs of hard-working people first.
She will also launch a scathing attack on Jeremy Corbyn's leadership of the Labour Party and call for a return to decency in political discourse.
"Millions of people who have never supported our party in the past are appalled by what Jeremy Corbyn has done to Labour," she will say.
"They want to support a party that is decent, moderate and patriotic. One that puts the national interest first. Delivers on the issues they care about. And is comfortable with modern Britain in all its diversity.
"We must show everyone in this country that we are that party.
"A party that conserves the best of our inheritance but is not afraid of change. A party of patriotism but not nationalism. A party that believes in business but is not afraid to hold businesses to account.
"A party that believes in the good that government can do but knows that government will never have all the answers.
"A party that believes your success in life should not be defined by who you love, your faith, the colour of your skin, who your parents were, or where you were raised – but by your talent and hard work.
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"Above all a party of Unionism, not just of four proud nations, but of all our people.
"A party not for the few, not even for the many, but for everyone who is willing to work hard and do their best."
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